ISD Team
19 Jul 2026

Sergey Stavisky, an associate professor of neurological surgery at UC Davis, has won the Chen Institute and Science Prize for AI Accelerated Research for developing an AI-powered speech neuroprosthesis that restores communication for people who have lost the ability to speak.

Key Achievement
  • An ALS patient who could no longer speak intelligibly received an implantable brain-computer interface (BCI).
  • AI models trained on his brain signals decode neural activity into phonemes, words, sentences, and synthetic speech modeled on his pre-ALS voice.
  • Results: Over 99% word accuracy, real-time performance (as fast as 30ms delay), ability to modulate intonation, and even sing.
  • The patient has generated millions of words (2.7 million over two years), enabling rich conversations with family, independent computer use, and continued full-time employment.
How It Works

Modern BCIs generate massive neural data that traditional methods can’t handle effectively. Stavisky’s team uses multiple AI models: one decodes brain signals into sound units, while others (leveraging large language models) turn them into fluent text or voice output.

Background & Future

Stavisky shifted from motor BCIs to speech after realizing communication is patients’ top priority. His work builds on advances in intracortical recording and machine learning. Future goals include a natural-sounding “high-fidelity surrogate voice,” smaller fully-implanted devices, and broader clinical applications for conditions like stroke, aphasia, and cerebral palsy.

The study

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