Artistic representation of a DNA helix intertwined with flowers and green leaves.

Many individuals feel chills when listening to music, reading poetry, or engaging with visual art, but these reactions vary widely from person to person. Such differences offer insight into how our brains and bodies process artistic experiences, highlighting the diversity of emotional responses. To explore the sources of this variation, researchers examined data from more than 15,500 participants with available genetic information to determine whether differences in DNA might help explain why some people are especially prone to intense emotional reactions.

Their analyses suggest that about 30% of the variation in experiencing chills is related to family-associated factors, with roughly one-quarter of that portion attributable to common genetic variants. Some of these genetic influences appear to span multiple forms of art—music, poetry, and visual art—and are linked to traits such as openness to experience and broad artistic interests. Other genetic effects may be specific to particular artistic domains. Overall, these findings indicate that genetics plays a meaningful role in shaping how strongly individuals respond to cultural experiences and lay the groundwork for future research on the biological basis of sensitivity to art and music.

Key Facts:

Genetic Contribution: Common DNA variants explain a meaningful share of why some people are more likely than others to experience aesthetic chills.
Family-Linked Effects: Roughly 30% of the variation in emotional responsiveness to art is associated with factors shared within families.
Personality Overlap: Certain genetic influences are connected to Openness to Experience, a personality trait tied to broad artistic interest across music, poetry, and visual art.
Art-Form Specificity: The findings suggest that some biological pathways are specific to particular art forms—indicating that genetic influences on responses to music may differ from those shaping reactions to visual art.
Brain Systems Involved: Aesthetic chills activate neural circuits similar to those involved in processing biologically significant stimuli, such as food or survival-related cues, underscoring the deep, fundamental impact of art on the human brain.

To the study

Share on